Clinician Oncology Hematology Expert for AI Healthcare Project
Overview
A remote contractor role for an experienced clinician in oncology or hematology to support a customer project at the intersection of AI and healthcare. You’ll review and author evaluation materials, judge the clinical defensibility of efficacy and safety conclusions, and ensure reported endpoints align with real-world clinical significance. You will translate complex clinical reasoning into clear, guideline-based rationales for non-clinical audiences using your domain knowledge and structured documentation. Key focus areas include dose escalation decisions, adverse event grading, and detailed outcome endpoints across oncology and hematology trials. CTCAE, RECIST, and Lugano criteria are core tools in this work.
What You'll Do6
- 1Author and review evaluation tasks grounded in clinical study reports, safety reports, and regulatory correspondence for oncology and hematology.
- 2Assess the clinical defensibility of efficacy and safety outcomes, ensuring reported endpoints and effect sizes reflect meaningful clinical impact.
- 3Apply expert judgment on dose escalation, toxicity handling, adverse event attribution, and coherence of patient narratives.
- 4Evaluate benefit-risk reasoning and the durability of conclusions in light of new safety events or protocol changes.
- 5Flag clinically implausible or internally inconsistent content and distinguish it from legitimate clinical variation.
- 6Provide structured, guideline-based rationales that clearly explain the validity or limitations of interpretations to non-clinical readers.
Requirements7
- 1Board certification or specialist registration in medical oncology and/or hematology with 5+ years post-training clinical experience.
- 2Direct involvement in clinical trials as investigator, sub-investigator, or sponsor-side medical monitor or safety physician.
- 3Proficiency with CTCAE grading and trial response criteria (RECIST, Lugano, IMWG, IWCLL, ELN) plus endpoints (ORR, DoR, PFS, OS, MRD).
- 4Hands-on experience with trial documents such as protocols, investigator brochures, CSRs, safety narratives, DSMP/IDMC materials.
- 5Strong written communication skills with the ability to explain clinical reasoning to non-clinical audiences.
- 6Experience in medical monitoring or as medical director on oncology/hematology programs and participation on IDMC/DSMB/adjudication committees.
- 7Track record of peer-reviewed publication or trial manuscript authorship; familiarity with AI-assisted clinical review tools is a plus.
Who Should Apply
The ideal candidate is a seasoned oncologist or hematologist with extensive trial exposure and a talent for translating complex data into clear, non-clinical explanations. This role suits a clinician who can rigorously appraise endpoints, toxicity, and risk–benefit reasoning. It is less suitable for those without hands-on trial experience, without board certification, or without experience documenting clinical ideas for regulatory or non-clinical audiences. Common rejection reasons include limited exposure to CTCAE and response criteria or minimal experience with trial documents and committee work.
Salary Insight
Pay ranges from $160 to $200 per hour; compensation details are provided upfront and discussed as part of the engagement.
Location
Required Skills
Application Tip
Highlight your trial leadership and specific endpoints you’ve managed (ORR, PFS, MRD) and cite a published manuscript or regulatory document where you contributed.
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How your application is processed
1Application received
Your resume and details are logged the moment you apply.
2ATS + eligibility screening
We check your profile against the role’s skills, seniority, and requirements.
3Employer sees qualified profiles only
Only candidates who clear screening move forward.
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