CRISPR Gene Editing SME

What You'll Do5

• Score and annotate AI answers to gene editing prompts for scientific correctness and the level of hazard they describe
• Judge whether a response handles a sensitive biological topic the way a trained researcher would
• Mark outputs that raise biosecurity or DURC concerns, or that misstate how a gene editing method works
• Write a short written rationale behind each annotation decision so reviewers can follow your reasoning
• Finish the assigned annotation set inside the one-week window at 10 to 20 hours per week

Requirements10

• Enrolled in or finished a PhD (second year or later) or a Master's program in molecular biology, genetics, synthetic biology, microbiology, virology, bioengineering, computational biology, or biomedical engineering
• Two or more years of hands-on bench work with CRISPR or another gene editing system
• Working knowledge of Cas9, Cas12 and Cas13, gRNA design through Benchling, CRISPick or CHOPCHOP, and cell line experiments
• Practical exposure to off-target analysis, including methods such as CIRCLE-seq or GUIDE-seq
• Preferred: research centered on disease or therapeutic uses of gene editing
• Preferred: hands-on work with base editing, prime editing, or gene drives
• Preferred: familiarity with biosafety policy, dual-use research of concern, or biosecurity questions
• Preferred: BSL-2 or higher lab clearance
• Preferred: Python or R skills for sequence analysis, bioinformatics, or BLAST work
• Preferred: ties to gene editing therapeutics companies or biosecurity research organizations

Who Should Apply

A molecular biology PhD student past year one, or a Masters researcher, who has spent at least two years at the bench with CRISPR/Cas systems and can read a model's answer on gene editing for both accuracy and dual-use risk. Prior exposure to biosafety policy or DURC review strengthens the case.

Salary Insight