Machine Learning Bioinformatics Expert - Remote Contract
Listing checked September 22, 2026 · pay as published by AfterQuery
Overview
AfterQuery seeks a bioinformatics machine learning expert for remote contract projects that pair machine learning with genomics, transcriptomics, and multi-omics data. Assignments arrive project by project over the next 2 to 3 weeks, with an expected 10 to 20 hours per week for work you accept. You will build models, assemble reproducible pipelines, and document methods for biological datasets such as sequence, expression, and proteomic data. The company is an early-stage Y Combinator-backed startup, and the role pays $150 to $200 per hour.
What You'll Do5
- 1Apply machine learning methods to genomic, transcriptomic, proteomic, and multi-omics datasets.
- 2Train, test, and tune models for variant calling, gene expression analysis, and pathway modeling.
- 3Build predictive models with supervised and unsupervised learning for biological systems.
- 4Design bioinformatics pipelines that include ML steps and support reproducible, scalable analysis.
- 5Write documentation that covers methodologies, model assumptions, and technical decisions.
Requirements7
- 1First-author publication in a peer-reviewed journal.
- 2Master's or PhD in bioinformatics, computational biology, computer science, data science, or another quantitative field.
- 3Proven skill in machine learning and bioinformatics, with work spanning sequence analysis, genomics, transcriptomics, or similar biological data.
- 4Ability to solve technical problems with little supervision.
- 5Familiarity with bioinformatics tools and workflows such as GATK, STAR, DESeq2, Nextflow, or Snakemake.
- 6Teaching or TA experience in bioinformatics, machine learning, or computational biology.
- 7Exposure to biological foundation models or large-scale omics ML frameworks such as scVI, DNABERT, or Enformer.
Who Should Apply
Candidates who hold a master's or PhD in a quantitative field and have at least one first-author peer-reviewed publication will match the core profile. The strongest applicants pair hands-on machine learning work with biological data experience in genomics, transcriptomics, or multi-omics, and they can point to pipelines built with tools such as Nextflow or Snakemake. This role suits independent researchers who enjoy short, focused contract projects and can commit 10 to 20 hours per week. People without a publication record, or whose ML background stays theoretical and lacks biological datasets, often score lower. A weak fit also appears when applicants cannot list programming languages, skip the GitHub profile, or submit a cover letter that does not connect their bioinformatics work to model development.
Salary Insight
Project-based pay runs from $150 to $200 per hour. That range sits well above typical academic postdoc or staff bioinformatics rates, and it aligns with specialized machine learning plus bioinformatics domain expertise rather than general data analysis work. The contract pays by project, so total earnings depend on how many assignments you accept and complete.
Pay and demand for Machine Learning & AI roles
AggregatedTypical pay
$75/hour
This role
$150–$200/hr
Most Machine Learning & AI roles pay $55–$100 per hour. This role's pay sits above that range.
Based on 543 similar roles that publish pay · 93 publish only a top rate; those count at the rate they gave
Rates shown per hour. Yearly and monthly pay converted; one-time fees and non-USD pay are not included.
- Live similar roles
- 601
- Listed in last 30 days
- 270
- Remote
- 97%
Hiring most right now: micro1 (270) · Mercor (90) · SME Careers (63)
Most requested skills · share of roles
- python17%
- technical writing8%
- llm evaluation8%
- data annotation7%
Figures from Machine Learning & AI roles live on NearSkill when this page loaded. A role can close before you apply, so check the listing itself.
Compare your resume against these rolesLocation
Compensation
$150–200/hr
Required Skills
Application Tip
List programming languages in a dedicated section, attach a portfolio link, and pair each language with a concrete bioinformatics or ML project. Then link the matching GitHub repository so reviewers can see commits, model code, or pipeline definitions, and in the cover letter, name your first-author publication and connect its methods to variant calling, expression analysis, or omics modeling.
See NearSkill jobs more often in your search
Application & verification flow
1Instant rubric match
Your resume is scanned against this role’s requirements to check qualification fit.
2Screened before the employer sees it
Only profiles that clear screening are passed on.
3Outcome by email
We notify you at the address on your resume once the screening is reviewed.
Similar open positions
Explore active roles that match your skills and interests.
AfterQuery
VerifiedMachine Learning Data Science Expert - Remote Contract
AfterQuery, an early-stage Y Combinator-backed company, seeks remote machine learning and data science experts for contract projects. The work matches tasks common to data science, ML engineering, AI research, or analytics roles, and it runs over the next 2 to 3 weeks on your own schedule. Projects arrive one at a time, with a listed baseline of 10 hours a week and expected commitments of 10 to 20 hours per week for accepted work. You will build and evaluate models, develop predictive models, and tune hyperparameter settings while documenting your methods. Pay starts at $60 per hour and can reach $100 per hour, and the project format helps you add real-world ML work to your portfolio.
Handshake AI
VerifiedBioinformatics AI Research Expert - Remote
Handshake AI runs a remote, part-time fellowship for computational biologists and bioinformatics scientists who want to shape how AI models reason about real research work. You will build expert-level problems that mirror genomics pipelines, NGS workflows, and sequence analysis, then assess model answers for technical accuracy and reproducibility. Your structured feedback shapes model development, and you choose your own hours with no minimum. The fellowship runs alongside a current role, so contributors can fit tasks around existing research or industry commitments.
Micro1
VerifiedMachine Learning Engineer – Remote Contract
This is a fully remote contractor role for a Machine Learning Engineer, paying $80–$150 per hour for roughly 15 hours per week. You will work on an AI training project that involves model development, training and inference systems, numerical computing, and performance optimization. The work is very coding heavy, and you must be comfortable using coding agents with Python in your daily workflow. Tasks include creating, solving, reviewing, and validating challenging ML engineering problems, often requiring you to implement or modify models, build reproducible training or inference pipelines, optimize memory or throughput, and debug numerical or system-level failures. The schedule is flexible, so you choose your hours and days, including weekends if you want.
Mercor
VerifiedMolecular Biology Expert - Remote UK Contract
A leading AI lab's GenAI group needs molecular biology subject matter experts to sharpen how foundational models reason about sequence design. You will work on DNA and RNA constructs such as primers, plasmids, guide RNAs, mRNA, and repair templates, then turn that knowledge into high-quality AI training data. The role sits with Cincinnatus LLC as a W-2 employer, with placement into the AI lab's extended workforce. You commit at least 20 hours across weekdays and help build CRISPR-related tasks, model evaluation rubrics, and written feedback that keeps training data accurate.
Micro1
VerifiedComputational Biology Expert Focused on AI Training and Biomed Data
The role focuses on guiding AI training with real-world computational biology input. You’ll evaluate and annotate AI system outputs in genomics, transcriptomics, and systems biology contexts, then benchmark performance against concrete biological benchmarks. You’ll document findings clearly and share actionable feedback with cross-functional teams. This is a remote contractor position that leverages deep domain knowledge to influence how models reason about biological data. Python and Bash scripting underpin your day-to-day work.
AfterQuery
VerifiedMolecular Biology Expert - Remote Contract
AfterQuery seeks life science researchers to help frontier AI labs measure how well models reason about molecular biology. You will design assay design and data interpretation scenarios, write reference answers that show the mechanism behind each result, and grade model output for pathway accuracy. The work stays inside biochemistry and molecular biology, so your scientific judgment matters more than volume. Commit about 10 hours per week, choose your schedule, and receive weekly pay through Stripe at $60 to $120 per hour.