Drug Discovery Specialist, Pharmacology & ADME/Tox

What You'll Do6

• Advise research and engineering teams on gaps in mechanism of action, target pharmacology, cellular pharmacology, ADME/Tox, and PK/PD so model performance improves.
• Create drug discovery tasks, benchmarks, and training examples that resist simple search, then write structured solutions for assay interpretation, compound liability review, and optimization planning.
• Review AI outputs and reasoning chains on discovery problems, flag errors in scientific logic, tool use, and factual claims, and return written technical feedback.
• Write specifications, grading rubrics, and verification steps for discovery data from external technical teams, and serve as the domain authority on data quality.
• Guide assay design, quality control, and failure-mode analysis, and check the biological and pharmacological soundness of model outputs.
• Work with other subject matter experts to keep training data consistent and accurate.

Requirements7

• PhD in pharmacology, pharmaceutical sciences, toxicology, DMPK, biochemistry, or a related field, or comparable research experience.
• 3+ years in early-to-mid stage drug discovery, pharmacology, DMPK/ADME, or toxicology at a pharmaceutical company, biotech, contract research organization, or academic drug discovery group.
• Hands-on work analyzing experimental data from in vitro ADME and safety assays, PK/PD studies, CRO assay readouts, or LC-MS bioanalysis, with a record of using that data to guide compound decisions.
• Comfort with PK/PD or data analysis software and scientific AI tools. No coding required.
• Availability for at least 20 hours per week on weekdays.
• Strong written communication and the ability to explain complex technical decisions in plain language.
• Nice to have: PK/PD or ADME modeling, grading rubric writing, benchmark task design, or evaluation of scientific AI models.

Who Should Apply

The ideal candidate has a PhD or equivalent research background plus at least three years of hands-on discovery work in pharmacology, DMPK/ADME, or toxicology. You have used assay data, PK/PD results, or LC-MS bioanalysis to guide compound decisions and can explain those calls in writing.

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